✦ Luna Orbit — Engineering (Non-Software)

Advisor/Senior Advisor Linker-Payload, Antibody-Drug Conjugate and Bioconjugation Engineering

at Eli Lilly

📍 US, Indianapolis IN Unknown 💰 $129K – $209K USD / year Posted March 13, 2026
Salary $129K – $209K USD / year
Type Full-Time
Experience mid
Exp. Years Not specified
Education Not specified
Category Engineering (Non-Software)

This role focuses on small molecule linker-payload and bioconjugation chemistry for ADC and AOC medicines, supporting process development and manufacturing of innovative biologics.

  • Develop linker-payload chemistry
  • Optimize bioconjugation processes
  • Scale-up unit operations
  • Improve purification techniques
  • Support medicines development

The position involves conjugation chemistry, unit operations, crystallization, chromatography, and flow filtration within the context of ADC/AOC development and pharmaceutical manufacturing.

The ideal candidate is a highly motivated bioconjugation and conjugation chemistry expert with experience in ADC and AOC development, process optimization, and unit operations within the pharmaceutical industry. They are collaborative, innovative, and skilled in small molecule-biologics interface challenges.

small molecule chemistrybioconjugationADCAOCconjugation chemistry
crystallizationchromatographic purificationprocess developmenttangential flow filtration
chromatographyflow filtrationspectroscopy
small molecule Linker-payloadADCAOCbioconjugationconjugation chemistryunit operationscrystallizationchromatographic purificationprocess developmenttangential flow filtration
small molecule chemistrybioconjugationADCAOCconjugation chemistryunit operationscrystallizationchromatographic purificationprocess developmenttangential flow filtration
collaborativeproblem-solvingmechanistic thinkingdata analysisinnovative
Industry Healthcare & Medical
Job Function Small molecule-biologics interface engineering for ADC/AOC
small molecule Linker-payloadADCAOCbioconjugationconjugation chemistryunit operationscrystallizationchromatographic purificationprocess developmenttangential flow filtrationsmall molecule chemistrybioconjugation developmentmedicines developmentpharmaceutical development

Lack of experience in bioconjugation or conjugation chemistry, No background in pharmaceutical development, Inability to work cross-functionally, No experience with ADC or AOC platforms

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