✦ Luna Orbit — Science & Research

Associate Principal Scientist (Associate Director) - Regulatory Affairs - CMC, Biologics

at Merck

📍 3 Locations Hybrid 💰 $142K – $224K USD / year Posted March 18, 2026
Salary $142K – $224K USD / year
Type Full-Time
Experience senior
Exp. Years 10+ years
Education Bachelor's in a science, engineering, or a related field
Category Science & Research

This role involves leading regulatory CMC strategies for biologics, preparing submissions, and ensuring compliance with global guidelines. The candidate will mentor staff and collaborate across departments.

  • Implement regulatory strategies
  • Prepare and submit CMC sections
  • Collaborate on global assessments
  • Mentor junior staff
  • Ensure compliance with regulations

Expertise in biologics regulatory CMC, IND/BLA submissions, global regulatory assessments, and post-approval changes. Knowledge of analytical development and quality assurance processes.

The ideal candidate is a senior regulatory affairs professional with over 10 years of biologics CMC experience, familiar with global regulatory strategies, IND/BLA submissions, and post-approval changes, capable of mentoring junior staff and leading regulatory assessments.

Biologics INDLicense Application (BLA) experience10+ years biologics CMC development or manufacturingregulatory CMC experience in pre-approval and registrationauthoring agency interactionsregulatory submissions
advanced degree in science or engineeringexperience with global regulatory strategiesmentoring junior staffglobal regulatory assessments
regulatory guidelinesglobal assessment policies
BiologicsCMCregulatory strategiesINDBLAglobal CMC guidelinesregulatory assessmentsagency interactionspost approval changesanalytical developmentquality assurance
CMCChemistryManufacturingand ControlsBiologicsINDBLAregulatory strategiesglobal CMC guidelinesregulatory assessmentsIND/BLAspost approval changesagency interactionsregulatory submissionsregulatory developmentregulatory complianceanalytical developmentquality assuranceprocess development
mentoringcoachingcollaborationcommunicationproblem-solvingattention to detailleadership
Industry Pharmaceuticals & Biotechnology
Job Function Lead biologics regulatory affairs and compliance
Role Subtype Regulatory Affairs Specialist
Associate Principal ScientistRegulatory AffairsCMCBiologicsINDBLAregulatory strategiesglobal CMC guidelinesregulatory assessmentsagency interactionsregulatory submissionspost approval changesregulatory complianceanalytical developmentquality assurance

Less than 10 years biologics CMC experience, Lack of experience with IND/BLA submissions, No global regulatory strategy experience, No mentoring or leadership experience

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