Associate Scientist II/Scientist I, Process Chemistry Separations

This role supports AbbVie’s Process Chemistry Chromatographic Separations Lab by developing and executing purification processes for small molecule, ADC, and peptide candidates. The scientist will handle laboratory and pilot-scale separations, analyze data, troubleshoot, and implement scalable methods under cGMP guidelines.

• Develop and execute purification processes for small molecule, ADC, and peptide clinical candidates
• Develop, troubleshoot, and modify chromatographic methods and purification protocols
• Conduct laboratory and pilot-scale tasks and analyze/interpret data
• Suggest and implement new or improved experimental protocols/techniques
• Support continuous process improvement while adhering to cGMP and safety/quality standards

You will develop and troubleshoot preparative chromatography methods and purification protocols, including scalable pilot-scale purification. The work includes purification of peptides, ADC drug-linkers, and chiral compounds, along with isolation of low-level API impurities using chromatography and spectral analysis under cGMP expectations.

The ideal candidate is an Associate Scientist II or Scientist I with a strong Separations Science background, hands-on experience developing and troubleshooting chromatographic methods, and the ability to execute purification processes from laboratory through pilot-scale. They are familiar with cGMP expectations for process execution and can analyze and interpret chromatography and spectral data to support R&D programs, with peptide experience a strong plus.