✦ Luna Orbit — AI & Machine Learning

Principal Enterprise Architect - AI & Agents

at IQVIA Holdings

📍 2 Locations Remote 💰 $118K – $328K USD / year Posted March 31, 2026
Salary $118K – $328K USD / year
Type Full-Time
Experience lead
Exp. Years 10+ years
Education Not specified
Category AI & Machine Learning

Principal Enterprise Architect - AI & Agentic Solutions defines, governs, and evolves enterprise architectures for AI-driven initiatives, focusing on scalable, standards-driven patterns across Azure and AWS, with strong governance and regulatory alignment.

  • Define and evolve enterprise reference architectures for AI; govern solution designs; provide architectural oversight for major AI initiatives; translate strategies into capability roadmaps; monitor AI trends and ensure regulatory alignment

Leadership in generative AI architecture, agentic capabilities, and enterprise data platforms; cloud-native delivery on Azure/AWS; reference architectures and reusable patterns; governance using EA tools (LeanIX/Ardoq/MEGA).

The ideal candidate is a senior enterprise architect with 10+ years of experience designing scalable generative AI and agentic solutions, strong cloud skills on Azure and AWS, and a track record of governance and platform consolidation in regulated industries.

10+ years of experience in enterprise or application architectureProven experience designing and scaling generative AI and agentic solutionsDeep technical knowledge of generative AI and agentic concepts (vector databasesRAGtool useMCP serversHITLevaluation frameworksmonitoringobservabilityLangGraph)Strong cloud architecture experience on Azure and/or AWSExpertise in modern integration styles (APIfirsteventdrivenmicroservices)Excellent communication and stakeholder managementExperience building business cases for modernization and platform consolidation
Healthcare or life sciences experienceHands-on partnership with CRO teamsProficiency with LeanIXArdoqMEGA
AzureAmazon Web ServicesLangGraphLeanIXArdoqMEGA
10+ years enterprise architecturegenerative AIagentic solutionsvector databasesRAGtool useMCP serversHITLevaluation frameworksmonitoringobservabilityLangGraphAzureAmazon Web Serviceslakehousedata governanceintegration patternsAPIfirstevent-drivenmicroservicesLeanIXArdoqMEGAGDPRHIPAAEU AI Act
Vector databasesRAGtool useMCP serversHITLEvaluation frameworksMonitoringObservabilityLangGraphAzureAmazon Web ServicesLakehouseData governanceIntegration patternsAPIfirstEvent-drivenMicroservicesLeanIXArdoqMEGA
LeadershipCommunicationInfluenceStakeholder managementMentoring

Preferred

LeanIX/Ardoq/MEGA familiarityFormal capability modeling certification
Industry Healthcare & Medical
Job Function Lead enterprise AI architecture across global platforms, establishing standards, patterns, and governance for responsible, scalable AI solutions
Role Subtype Principal Enterprise Architect - AI & Agentic Solutions
Tech Domains Azure, Amazon Web Services, LangGraph, Data governance, APIfirst, Event-driven, Microservices, Vector databases, RAG, HITL
principal enterprise architectai & agentic solutionsenterprise architecturegenerative aiagenticvector databasesragtool usemcp servershitlevaluation frameworksmonitoringobservabilitylanggraphazureamazon web serviceslakehousedata governanceintegration patternsapifirstevent-drivenmicroservicesleanixardoqmegagdprhipaaeu ai actgenerative AIAzureAmazon Web ServicesLangGraphMEGA

Less than 10 years in enterprise/application architecture, No experience with generative AI or agentic systems, Lack of cloud experience on Azure or AWS, Inability to engage senior stakeholders

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