✦ Luna Orbit — Data & Analytics

Senior Director, Clinical Data Science

at Centene

📍 38 Locations Hybrid 💰 $185K – $352K USD / year Posted April 15, 2026
Salary $185K – $352K USD / year
Type Full-Time
Experience executive
Exp. Years 8+ years years
Education Bachelor's Degree in a quantitative discipline such as Statistics, Biostatistics, Informatics, Mathematics, Computer Science, Public Health, or Economics or four (4) years of experience in lieu of degree. Master's Degree preferred.
Category Data & Analytics

Leads enterprise clinical data science strategy, building and deploying predictive and AI models to support clinical decision-making. Responsible for rigorous evaluation of clinical programs using causal inference and for ensuring model governance, monitoring, and responsible AI practices.

  • Lead enterprise clinical data science strategy
  • Develop and deploy predictive/AI models for clinical risk and care management
  • Evaluate clinical programs using causal inference and quasi-experimental methods
  • Establish model governance, monitoring, and performance management
  • Build, lead, and mentor a data science team

Focuses on advanced analytics and machine learning, including deep learning and transformer-based models applied to large healthcare datasets. Applies quasi-experimental evaluation methods such as treatment effect modeling, propensity score matching, and difference-in-differences, and builds governance frameworks for monitoring model performance and fairness.

The ideal candidate is an executive-level clinical data science leader with 8+ years of data analysis, statistics, and related experience. They have deep experience building and deploying predictive and AI-driven models in healthcare, including rigorous causal inference and quasi-experimental program evaluation. They lead teams, establish model governance and monitoring, and partner with clinical and operational stakeholders to embed models into care management workflows.

8+ years years of data analysisstatistics or related experienceDeep experience developing and deploying predictive and AI-driven modelsCausal inference and quasi-experimental methodsTreatment effect modelingPropensity score matchingDifference-in-differencesModel governancemonitoringand performance managementDeveloping and deploying advanced models for clinical/care management interventionsLeadership of a data science team
Predictive modelingMachine learning innovationCausal inferenceProgram evaluation methodologiesAI-driven modelsDeep learningTransformer-based modelsTreatment effect modelingPropensity score matchingDifference-in-differencesModel governanceModel monitoringPerformance managementRegulatory complianceResponsible AIFairness
Predictive modelingMachine learning innovationCausal inferenceProgram evaluation methodologiesAI-driven modelsDeep learningTransformer-based modelsTreatment effect modelingPropensity score matchingDifference-in-differencesAnalytic frameworksClinical risk modelingClinical decision-makingMember stratificationCare management prioritizationHigh-risk and rising-risk identificationAvoidable utilization modelingChronic condition progression modelingCost savings quantificationROI (return on investment) quantificationModel governanceModel monitoringPerformance managementRegulatory complianceFairness and responsible AI practicesEmbedding models into operational workflows
LeadershipTeam buildingMentoringCross-functional collaborationStakeholder partnershipCommunication with senior stakeholdersTranslating business and clinical priorities into scalable solutionsEnsuring alignment with operational workflowsAttention to compliance and fairness
Industry Healthcare
Job Function Executive leader driving enterprise clinical data science, predictive modeling, and causal program evaluation
Role Subtype Executive leader, data science
Visa Sponsorship No
Senior DirectorClinical Data Scienceadvanced analyticsmachine learning modelspredictive modelingAI-driven modelsclinical decision-makingcausal inferencequasi-experimental methodstreatment effect modelingpropensity score matchingdifference-in-differencesdeep learningtransformer-based modelsprogram evaluation methodologiesmodel governancemodel monitoringperformance managementregulatory complianceresponsible AIfairnessROI (return on investment)care management prioritizationchronic condition progression

Must have 8+ years years of data analysis, statistics or related experience, Must demonstrate causal inference and quasi-experimental methods (treatment effect modeling, propensity score matching, difference-in-differences), Must have experience developing and deploying predictive/AI models for clinical risk and care management

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